Smartphone Medicine in Solving Long COVID

Currently, the American CDC reports 18 million long COVID cases in the US, and 65 million globally, with these numbers likely rising from the millions of developing COVID-19 cases, with thousands dying each month despite mass vaccinations [1]. The sources express concern that high long COVID-19 numbers highlight the puzzle of multisystemic pathology, the human and economic tolls, as well as the stress on healthcare systems. Despite the failure of the NIH, after spending

$1.6B, and many studies to establish the responsible causes and effective treatments with drugs or alternatives, hundreds of more studies are in the process of using the same, pharmaceutically focused model of molecular biology [2]. As benevolent lawmakers, such as US Senator Bernard Sanders (VT), who seek to appropriate 10 billion more dollars for the challenge, the medical community shuns reexamining this model, which, besides long COVID-19, also fails other chronic infections. Among the latter are EBV, HSV-1, HSV-2, herpes zoster, HIV, H. Pylori, Lyme disease, and co-infections. All of these carry essentially the same gaps as long COVID: unknown exact causes for their chronicity and failure of the antimicrobial drugs. While the pharmaceutical model emphasizes its rigor in applying the scientific method, it continues to overlook the need to reassess whether its critical initial stage—defining the research focus—is optimally inclusive of background research and knowledge that would offer superior solutions to problems. Concerning infections, including COVID-19, an extensive toxicological background indicates more severe outcomes and poor recovery due to compromised local and systemic immunity by toxicants [3-4]

These may also cause an overactive autoimmune response, with dysfunction in multiple organs, which has also been detected in long COVID-19, as the overall pathogenicity of these agents in COVID-19 and other chronic infections was emphasized [5-11].

The data of medical toxicology and the US Environmental Protection Agency list these agents, particularly heavy and other metals, as direct and indirect immunosuppressants, through invasion of the immune system and ones that support it, such as endocrine, gastrointestinal, neurological, and others [12-13]. Additionally, the disruption of the cytoskeleton by toxicants, including the mitochondria, and epigenetic and intercellular communications, further perturbs global homeostasis through the interconnectedness and interdependence of body systems [14]. Also considering the fact that thousands of pollutants commonly act in unpredictable and impossible for laboratory assessments to establish combinations, the consequent multisystemic pathogenesis eludes the ability of the specialty-confined research model to match it [15]. The problem of public protection from pollutants has failed, as according to the Harvard University EPA Working Group 2007 Report, traces of hundreds of environmental pollutants have been found in the bodies of 100% of tested Americans, which can be extrapolated to all industrialized nations. The ubiquitous presence of toxicological agents in modern societies, with common internal presence from birth and increasing thereafter through nursing, in baby and regular food, air, and water, significantly raises their pathogenic potential in chronic infections and diseases [16-21].

The most ubiquitous toxicants, mercury, lead, and the rest of the heavy and other metals, carry the highest pathogenicity that can produce any of the immunological dysfunctions that have been encountered in long COVID and other chronic infections. Mercury, which is the most toxic non-radioactive element, exerts multisystemic, including immune pathologies, from common exposures to fossil fuels, seafood, and silver amalgam fillings [22-26]. The presence of mercury since childhood is correlated with silver amalgam fillings, whose utilization is global [27].

Metallic dental restorations, particularly silver amalgams, and metals in general that are widely present in modern populations are also electromagnetic conductors that act as internal receiving antennas for pervasive electromagnetic fields, resulting in mutually enhanced pathogenicity.

This further exacerbates stress on the immune, central nervous, and other systems [28-33].

Besides the ubiquitous exposure starting neonatally, the pathogenicity of metals is particularly ominous because these are not metabolizable, are only partially excreted, and cause deep, down-to-the-DNA, cellular penetration [34].

In addition to this relevant toxicological research being essentially void in medical training, even when laboratory screening is performed for mercury, other metals, and toxicants, it poorly correlates with their presence in the seed of pathologies and internal organs [24,34].

Relevant background information also lists other factors that compromise immunity, such as the perturbed gut microbiome and dysbiosis, linking them to complications and mortality in COVID-19 [35]. Subclinical opportunistic infections of the candida genus, with evasion from immune cells, their suppression, and apoptosis, can be commonly present among not severely immunocompromised populations as the result of ubiquitous consumption of antibiotics and simple sugars [36-38]. Antibiotics themselves undermine host resistance by damaging immune cells and their response and have been associated with numerous chronic diseases, including cancer [39-41]. Another common subclinical infection, helminth parasitosis, is also prone to immunomodulation [42]. As a Candida species, it does not receive proper clinical vigilance, and stool diagnosis is compromised by varying laboratory sensitivity methods and irregular egg shedding. Chronically stressed and depleted by toxicants and infections, the endocrine system and limbic zone further contribute to immune deficiency and exacerbate the overall pathophysiology of long COVID, which also presents with associated cortisol deficiency [43].

Besides endocrine dysfunctions not being commonly suspected in chronic infections, even when obtained, the hormonal profiles falling in the low normal ranges may not necessarily correlate with a patient’s individual physiologic normal range, leading to the potentially overlooked importance of hypofunctioning hypothalamic-pituitary-adrenal axis. To address these limitations in managing chronic infections and long COVID, the reported cases were examined through another critical background research factor: the submolecular ontological level of both living organisms and pathogens. Physicists refer to this level as depth that addresses the limitations of the specialty-focused molecular research model, by rendering the detection of disease etiology more accessible and treatment more successful [44]. This level is fundamental and formative to molecular structures, representing their very identity, and is clinically indistinguishable from the material ones being used in practice and research. Its noninvasive diagnostic ability to access the seat of diseases, the internal organs, via the phenomenon of resonance, offers great potential.

The reason Einstein referred to our visible material molecular reality as an “optical illusion,” is based on the well-accepted matter-energy duality principle of all substances. By illusion, he implied that our eyes cannot discern the fact that matter is actually condensed energy fields, as his famous E = mc² equation postulated. This also applies to the living, microbes, and human organs, including the DNA. These possess electric, electromagnetic, magnetic, and electronic properties that are reflected in the sciences of quantum biology, magnetic biology, bioelectronics, and biophysics, among others. Physics, materials science, and water science deem water to be an ideal medium for the delivery of therapeutic signals at the level of depth. Due to its semiconducting and other physical and chemical properties, water is readily programmable with information of the molecular field, of any pathogen, organ, or cellular structure for which specific pharmaceuticals do not exist, rendering it to be “tomorrow’s wonder drugs” [45]. Also, neither programming nor therapeutic actions require the addition of chemical, biological, or genetic agents that favor safety and its related shortened testing time. Water also constitutes an important internal biophysical regulator of the body.

Nobel laureate in physics, Brian Josephson, and Nobelists in medicine, Albert Szent-Györgyi and Luc Montagnier, either supported the validity of programmed water or commented on the importance of the physics of water and organisms in biology and medicine. Szent-Györgyi warned that biology was studying dead matter without engaging the physics of organisms and water.Immunologist Benveniste, who first registered the immune response to water programmed through a homeopathic preparation platform, named this paradigm digital biology [46].

Referring to the submolecular level of the living that is innately receptive to energetic signals, physicists posited that biology and medicine are only physics [47].